Infectious Diseases Detection Technology, for R&D partnering and platform licensing:

"Take a New Look at Microbial Detection"

HGS currently enjoys a rapidly developing base of R&D Partners and Licensees for its simplification technology. The Key application of this is for the detection of infectious diseases with molecular assays.  This is a growth area for the Co. that is attracting attention from around the world. We invite you to contact us for enquiries regarding our Partnering and Licensing programs on info@geneticsignatures.com

Key features of our Microbial Detection Technology:

Significantly Improved Specificity

• Statistically significant improvement (p=0.001) in false positives vs. current FDA standard for HPV testing (Hybrid Capture 2 method)
• For high-risk HPV testing; 13 high risk targets are clearly identified from a complex background of low-risk virus
• Ability to drill down from broad microbial class (e.g. gram negative/gram positive.) into specific genus and species detection levels.

Multi-Target Screen; Single Reaction

• Achieve detection of multiple microbial strains in a single reaction without the need for multiplexing
• Single consensus primer detects presence of any/all variants of species of interest, with high degree of specificity. One well, one reaction, one tube - a simple yes/no result
• Also able to genotype specific species present with a simple step using same purified sample as used for the screening assay.

4 to 3 Simplification; Revolutionary.

• Reduces 4 genomic bases to 3 bases (ACTG to ATG) - “4 to 3” conversion to create a greatly simplified and non-natural genome
• Virtually eliminates sample nucleic acid degradation usually associated with the chemical process used to achieve “4 to 3” (bisulphite conversion)
• Allowing for the choice of any region in the genome, for greater specificity and unique primer design for microbial detection